13 Inheritable diseases in Old English Sheepdogs
X linked blood clotting disorder 2.Cataract Defective eyesight due to opacity of lens 3.Ciliary Dyskinesia Immotile cilia.Dogs contract recurrent pneumocid disease.May be situs invertus viscerum in 50% of affected animals. 4.Sensorineural deafness Deafness with microphthalmia and other developmental defects. 5.Cryptorchidism Failure of descent of testes. Coupled with failure in maturation. 6.Hip dysplasia Lameness in hind legs and gait problems 7.Immune mediated thrombocytopenia Auto-immune attack on,and loss of,platelets. Made lead to clotting problems. 8.Mitochondrial myopathy Exercise intolerance,exercise induced metabolic acidosis 9.Cystic bone lesions Benign cystic bone lesions. 10.Cerebellar degeneration Progressive gait abnormalities,subsequent ataxia and tremors. 11.Portosystemic shunt Vascular shunt bypassing liver leading to toxic encephalitis. 12. X - linked myopathy Dystrophin deficienct muscular distrophy.Muscle weakness and wasting. 13.Ivermectin sensitivity Neurotoxic reactions and signs of gastrointestinal tract toxicosis and myelosuppression to ivermectin and other drugs that are substrates of P-glycoprotein. These diseases are written straight from University of Cambridge Veterinary School's website. If you do research the information is out there for anyone to read. I hope this can help others learn more about the inheritable diseases that plague our breed.All breeds have their share of inheritable diseases. Robin |
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gumbo41 wrote: 1.Hemophilia A X linked blood clotting disorder 2.Cataract Defective eyesight due to opacity of lens 3.Ciliary Dyskinesia Immotile cilia.Dogs contract recurrent pneumocid disease.May be situs invertus viscerum in 50% of affected animals. 4.Sensorineural deafness Deafness with microphthalmia and other developmental defects. 5.Cryptorchidism Failure of descent of testes. Coupled with failure in maturation. 6.Hip dysplasia Lameness in hind legs and gait problems 7.Immune mediated thrombocytopenia Auto-immune attack on,and loss of,platelets. Made lead to clotting problems. 8.Mitochondrial myopathy Exercise intolerance,exercise induced metabolic acidosis 9.Cystic bone lesions Benign cystic bone lesions. 10.Cerebellar degeneration Progressive gait abnormalities,subsequent ataxia and tremors. 11.Portosystemic shunt Vascular shunt bypassing liver leading to toxic encephalitis. 12. X - linked myopathy Dystrophin deficienct muscular distrophy.Muscle weakness and wasting. 13.Ivermectin sensitivity Neurotoxic reactions and signs of gastrointestinal tract toxicosis and myelosuppression to ivermectin and other drugs that are substrates of P-glycoprotein. These diseases are written straight from University of Cambridge Veterinary School's website. If you do research the information is out there for anyone to read. I hope this can help others learn more about the inheritable diseases that plague our breed.All breeds have their share of inheritable diseases. Robin Oh boy, so many of the diseases I'm learning about in Humans right now also in sheepies... I'm assuming cryptorchidism in sheepies also cause testicular cancer.... Thanks for the list |
| This list is surely not comprehensive; do these diseases represent the top 13 inheritable diseases? Are these most common for other breeds as well? |
| If you are asking me... I copied this from, University of Cambridge Vet, website. Obviously, the order they are listed is not the most prevalent disease. From what I know,hip dysplasia and certain cancers are the number 1 placements. Comprehensive-no,you would have to read about each disease. As far as, does these diseases plague all breeds,I do not know,but again, on the Cambridge website, you can go look up any breed, as I looked up,Old English Sheepdogs, a few years ago. I wrote this as a reference. Robin |
Thank you for taking the time to share this info!  |
| Hip Dysplasia is number one placement in all Large and giant breeds. Kathy the list is not accurate for OES, say for instance Hemophilia, fairly rare in OES but rife in GSD and Dobermans. Cataracts, any breed can be afflicted with these, juvenile ones and just from old age, no mention of "PRA" which was rife in the breed years ago and improved immensley over time with proper screening and excluding dogs and lines from breeding programs that have produced or had PRA, to lessen the risk which now is fairly low in the breed. PRA is more of a problem in the poodle breed then OES but no mention of that on the list compiled as PRA being detected in OES just cataracts which can happen in any breed of dog. Crytochidism can afflick any male of any breed even a mix. And so on all listed is related to any breed that can crop up. Invermectin sensitivity extemely high in collie breeds and because it is thought OES have collies in there background awareness is needed there. Not very often do you hear of an OES being sensitive to invermectin it has been detected but rate of being sensitive to it is extemely low. The OESCA has a more acurate and better list of surveyed health results on OES and what is known problems in the breed. Anyone wanting to know can click on that link for what are the main top hereditry health problems in the breed. I wonder where that university got its data from and how many OES were surveyed over how many years for that so called top list they compiled. Some of those listed above are very low stats to be listed as top problems in the breed. But yes any breed of dog, wether that be mixed or pure bred can suffer from any of the hereditry afflictions above  . |
lisaoes wrote: Kathy the list is not accurate for OES, say for instance Hemophilia, fairly rare in OES but rife in GSD and Dobermans. . All Kathy said was thanks for posting  I am about to hang up my cheerleading shoes |
| Wouldn't a link directly, to the OESCA, health page,be helpful for others? I stumbled upon this list from a nice lady from the raw fed chat list a few years ago,when reaching out for help with the Hemophilia. Just recently I have learned that there have been cases of Hemophilia, but it seems it is not discussed,openly. Anyway, thank you Lisa, for responding with your knowledge. Dr.Dodds had told me that some of these diseases,such as Hemophilia, can skip generations and then rear their ugly head. Someone more knowledgeable than me can compile a more comprehensive list. It cannot hurt,only help. Robin |
| Pom poms Kathy...get it right..LOL! I hear ya, loud and clear!!!! |
jcc9797 wrote: This list is surely not comprehensive; do these diseases represent the top 13 inheritable diseases? Are these most common for other breeds as well? Sorry kathy got the wrong name should of been the answer to jcc797 Ooops that is what happens when one is in KAOS packing up a house with only a week and a half left to get out  Was just popping in and reading too fast inbetween packing   |
lisaoes wrote: jcc9797 wrote: This list is surely not comprehensive; do these diseases represent the top 13 inheritable diseases? Are these most common for other breeds as well? Sorry kathy got the wrong name should of been the answer to jcc797 Ooops that is what happens when one is in KAOS packing up a house with only a week and a half left to get out Was just popping in and reading too fast inbetween packing No worries Lisa..I was just trying to be a positive camper! Happy packing....yuck!  |
lisaoes wrote: jcc9797 wrote: This list is surely not comprehensive; do these diseases represent the top 13 inheritable diseases? Are these most common for other breeds as well? Sorry kathy got the wrong name should of been the answer to jcc797 Ooops that is what happens when one is in KAOS packing up a house with only a week and a half left to get out Was just popping in and reading too fast inbetween packing Thanks Lisa. I knew this list wasn't comprehensive nor necessarily accurate, thus me questioning it. I wanted to give Robin an opportunity to clarify .Still, Robin, thank you for posting this. Definitely something to help prod more research. |
| I just feel if this site can educate others, it is a good thing.I have had to experience some not so nice health issues myself.Believe me when I tell you it is heartbreaking and can make you feel helpless. However, after the initial shock and the pity party was over, I looked for a reason it happened to me. What kept popping in my mind was to do more research on the lineage of any dog that I was going to breed, along with all the proper tests available.When you know better you do better,from the mouth of a very wise woman.I learned a BIG lesson, however, even with all the research and all the proper testing,I discovered health issues can still pop up,unfortunately. Some diseases are easier than others to identify before breeding. The reason I chose the Cambridge website, was because, it was the only place on the internet that listed Hemophilia. Producing life is never going to be perfect,as much as we would hope for it to be. Do you know of the perfect dog, I know all of you are going to say mine,just like I would. But seriously,I do not,all have some sort of flaw. Lastly, I am by no means an expert on this breed,still learning something new after being owned by these furballs for over 25 years. Robin |
| Robin you never stop learning, having this breed since 1976 am still learning and always progressing in learning about the breed. Those that say they know everything are wrong, each day, week, month, year or years always something to learn and advance on what they say the good, the bad and the down right ugly. We can only try to do our best to ensure the advancement of the breed. And no, no OES is 100% perfect to the breed standard all OES have minor faults, in regard to breeding that perfect OES, but the guidelines of the breed standard only help to correct what one is looking for to perfect, enhance or correct. Anything that crops up from prior generations health wise is an unknown quandrum  , but if something does down the track after maybe many years rears up in something produced then it takes to exclude those lines and start again if one cant work out where it came from. Nothing is perfect in life but with testing, trying to breed to the breed standard and not having tunnel vision when it comes to ones own lines and stock and accepting if something goes scew whiff to start again with different blood lines or research to see where it has popped up from, then it can only enhance the health and well being of the breed.No breeds are excluded from where things can go wrong over the years but being aware if something does pop up, taking the right steps not to repeat that mistake and moving on is a bonus to the breed. I say regardless how long you have been in the breed or any breed regardless, you never stop learning, And yes you are right too, producing life if you care is never going to be perfect, but recognising that and moving on wether that is starting again or not and researching as much as you can is what is important for the breed and any breed regardless. |
| I could not of said it better, Lisa. Thank you, for taking the time away from your packing, to respond to this thread. Give that hunky, beautiful, blue eyed boy of yours a warm belly rub! Robin |
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